IFA research

IFA research

The new ESICM Early Enteral Nutrition Guidelines



TOPMAST TRial - TOnicity of Perioperative Maintenance SoluTions (TOPMAST-1)

Protocol -  https://clinicaltrials.gov/ct2/show/NCT03080831

Maintenance fluid use is very variable in the perioperative setting

Randomised controlled trial of intravenous maintenance 

Introducing TOPMAST, the first double-blind randomized clinical trial specifically dedicated to perioperative maintenance fluid therapy in adults


Fluid use in resource poor countries

Perioperative populations are not homogeneous https://academic.oup.com/bja/article/117/3/402/1744328

Strategies for Intravenous Fluid Resuscitation in Trauma Patients https://link.springer.com/content/pdf/10.1007%2Fs00268-016-3865-7.pdf

South African colleagues would eventually use colloids (including HES) in hypotensive patients.

Cardiac output monitoring is not available on a regular basis!

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